Question- How does spatial organization of cells relate to sectored phenotypes? Specifically, does division via budding impact colony organization?
S. Cerevisiae divide by budding.
Most models do not include budding process. Our model does.
How do we quantify the impact of budding on colony morphology?
In the past, two metrics have been traditionally used. Colony sparsity and expanse.
Okay, but what about colony organization?
Delaunay Triangulation partitioned by subcolony Graph
Lineage Tree Graph
Graph Intersection of Delaunay and Lineage Graphs
Degree of the Intersection graph (magenta) is higher when budding is included.
The number of lineage edges preserved in the intersection graph is higher when budding is included.
Question- How does this impact sector like structures in the colony?